SDHB purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： SDHB purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： SDHB purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00006390-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human SDHB protein.
- Immunogen:
- SDHB (NP_002991.2, 1 a.a. ~ 280 a.a) full-length human protein.
- Sequence:
- MAAVVALSLRRRLPATTLGGACLQASRGAQTAAATAPRIKKFAIYRWDPDKAGDKPHMQTYEVDLNKCGPMVLDALIKIKNEVDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTNLNKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDESQEGKQQYLQSIEEREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKEKKASV
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- SDHB MaxPab rabbit polyclonal antibody. Western Blot analysis of SDHB expression in human kidney.
- Protocol Download
- Western Blot (Cell lysate)
- SDHB MaxPab rabbit polyclonal antibody. Western Blot analysis of SDHB expression in HeLa.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of SDHB expression in transfected 293T cell line (H00006390-T04) by SDHB MaxPab polyclonal antibody.
Lane 1: SDHB transfected lysate(31.60 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 6390
- GeneBank Accession#:
- BC007840.2
- Protein Accession#:
- NP_002991.2
- Gene Name:
- SDHB
- Gene Alias:
- FLJ92337,IP,PGL4,SDH,SDH1,SDHIP
- Gene Description:
- succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq
- Other Designations:
- OTTHUMP00000002396,OTTHUMP00000044624,iron-sulfur subunit
- Gene Pathway
- Alzheimer's disease
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Citrate cycle (TCA cycle)
- Huntington's disease
- Metabolic pathways
- Oxidative phosphorylation
- Parkinson's disease
- Related Disease
- Abdominal Neoplasms
- Adrenal Gland Neoplasms
- Bone Neoplasms
- Carcinoma, Medullary
- Carcinoma, Renal Cell
- Cardiovascular Diseases
- Carotid Body Tumor
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Glomus Jugulare Tumor
- Glomus Tumor
- Hamartoma Syndrome, Multiple
- Head and Neck Neoplasms
- Hippel-Lindau Disease
- Infertility, Male
- Kidney Neoplasms
- Lymphatic Metastasis
- Multiple endocrine neoplasia