新型冠状病毒科研试剂
为了支持武汉新型冠状病毒相关研究和治疗产品开发,安必奇生物成立了专项工作小组,开展新型冠状病毒的研究。我们很快拿到了病毒基因序列信息,并研发生产出新型冠状病毒主要受体-ACE2蛋白产品,用于新型冠状病毒科学研究。
ACE2蛋白产品:
- ACE2-239H (Fc region of human IgG1)
- ACE2-185H (Fc region of mouse IgG1)
- ACE2-736H
同时,我们正在积极制备2019-nCoV S1蛋白,届时可与ACE2蛋白配套供应。我们密切关注新型冠状病毒研究动态,逐步提供更多科研试剂满足新型冠状病毒研究。
产品信息:
| 产品名称 | Recombinant Human ACE2, Fc tagged | 
| 货号 | ACE2-239H | 
| 产品信息 | Recombinant Human ACE2 extracellular domain precursor (Met 1-Ser 740) (NP_068576.1), fused with the Fc region of human IgG1 at the C-terminus, was produced in Human Cell. | 
| 来源 | Human cells | 
| 成分 | Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5 | 
| 分子量 | The recombinant human ACE2/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 961 amino acids and predicts a molecular mass of 110.3 kDa. As a result of glycosylation, the rhACE2/Fc monomer migrates as approximately 145-150 kDa band in SDS-PAGE under reducing conditions. | 
| 内毒素 | < 1.0 eu per μg of the protein as determined by the LAL method | 
| 纯度 | >90 % as determined by SDS-PAGE | 
| 产品名称 | Recombinant Human ACE2 Protein, Fc-tagged | 
| 货号 | ACE2-185H | 
| 产品信息 | Recombinant human ACE2 (NP_068576.1) (Met1-Ser740) was expressed with the Fc region of mouse IgG1 at the C-terminus. | 
| 来源 | HEK293 | 
| 成分 | Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol | 
| 分子量 | The recombinant human ACE2 consists 957 amino acids and predicts a molecular mass of 110 kDa. | 
| 内毒素 | < 1.0 EU per μg of the protein as determined by the LAL method | 
| 纯度 | >90 % as determined by SDS-PAGE | 
| 产品名称 | Recombinant Human ACE2, His-tagged | 
| 货号 | ACE2-736H | 
| 产品信息 | Recombinant human ACE-2 produced by transfected human cells is a secreted protein with sequence (Gln18-Ser740) of human ACE-2 fused with a polyhistidine tag at the C-terminus. | 
| 来源 | HEK293 | 
| 成分 | Supplied as a 0.2 μM filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.1mM ZnCl2, 10% Glycerol, pH 7.5 | 
| 生物活性 | Specific Activity is > 800 pmol/min/μg as measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH | 
| 内毒素 | Less than 0.1 ng/μg (1 IEU/μg) | 
| 纯度 | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE | 
